Antimicrobial Resistance

A Global Patient Consensus Statement and Call to Action on Antimicrobial Resistance

Our Concern

Antimicrobial therapies, including antibiotics, are powerful medicines that prevent and treat infections caused by pathogens including bacteria, fungi, viruses, and parasites. As with most medicines, these life-saving agents bring both benefits and risks, and must be used carefully, only when needed.

Antimicrobial resistance (AMR) occurs when these pathogens change over time and no longer respond to medicines, making infections harder to treat and increasing the risk of disease spread, severe illness and death. As a result, the medicines become ineffective and infections persist in the body, increasing the risk of spread to others. AMR is an increasingly serious public health threat, risking the effective prevention and treatment of infections.

AMR is estimated to be responsible for at least 700,000 deaths globally each year. In the US alone, at least 2.8 million people get an antibiotic-resistant infection and more than 35,000 people die, while in Europe, 33,000 people die from AMR each year. In India, 58,000 neonatal sepsis deaths were attributed to drug resistant infections in 2013, and in Japan, drug-resistant bacteria killed more than 8,000 people in 2017.

In China, AMR is expected to cause 1 million premature deaths annually by 2050; across Latin America and Africa, more than 800,000 deaths are expected to be due to AMR by 2050. OECD estimates that annual costs of AMR could be up to $3.5 Billion.

Addressing AMR requires concerted efforts by all stakeholders. We, as patients, patient caregivers, patient advocates and patient organisations have a goal to preserve effectiveness of antimicrobial medicines for as long as possible, so that they can be successfully used in treatment of infections, as well as to advocate for rational use and equitable access to existing and new anti-infective medicines and vaccines for everyone, everywhere.

Key Issues

Need for Increased AMR Awareness and Strengthened Health Literacy
Low awareness of AMR as a public health crisis among patients and public. Education on antibiotic stewardship and appropriate use.
Need for Improved Diagnosis and Evidence-Based Solutions
For any infection (bacterial, fungal, viral, parasitic) use the appropriate antimicrobial AMR patient data registries AMR surveillance systems.
Need for a Patient-Centered Approach In R&D and Access
Economic challenges for development of new antibiotics. Availability of and access to new medicines.
Need to Strengthen Holistic Public Health Measures
General infection prevention and control measures (e..g., vaccines, hygiene, etc.). Environmental impact and proper disposal of unused antibiotics.

Call to Action

We, the patient community, pledge to support actions to address AMR through:

Raising AMR Awareness And StrengthenHealth Literacy

Educate people who use antimicrobials and support the education of healthcare providers who prescribe and dispense them on actions they can take to reduce resistance, ensuring the right antimicrobial is prescribed according to clinical guidelines, and facilitating patient-clinical dialogues.

Advocating For Evidence-Based Solutions

Support the development and implementation of diagnostic tests to verify bacterial vs. viral, fungal or parasitic infection and support patient registries to gather antimicrobial usage data.

Ensuring a Patient-Centered Approach in Antimicrobial Development and access

Collaborate in efforts to research and develop new antimicrobials, vaccines, technologies, diagnostics and sustainable investment in AMR-relevant innovation, including promoting clinical trial involvement among a diverse patient community. Support equitable access to new antibiotics across all regions.

Strengthening public health measures

Add AMR in infection prevention educational programs that include measures such as sanitation, hand washing, vaccination, food and water safety, and antibiotic use in agriculture – all of which can decrease the spread of microorganisms resistant to antimicrobial medicines (in schools, healthcare facilities, animal farms, etc.). Educate the general public on the proper disposal of antimicrobials to reduce environmental impact and provide a ‘patient voice’ to the development of consumer-discharge standards.

Sign the Statement and Call to Action

AMR Global Patient Advisory Group

Mariano Votta

Mariano Votta

Cittadinanzattiva/Active Citizenship Network

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Neda Milevska-Kostova

Neda Milevska-Kostova

International Alliance of Patients' organizations

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Christine Verini

Christine Verini

Cancer Care

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Thomass Heymann

Thomass Heymann

Sepsis Alliance

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Daniel Gallego

Daniel Gallego

Federación Nacional de Asociaciones ALCER [Association for the Fight Against Kidney Diseases]

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Danjuma Adda

Danjuma Adda

World Hepatitis Alliance

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Signatories



Individuals

98

Pilar Arrossagaray

Estefania Malassisi

Liliana Tieri

Argentina

Trevor Lithgow

Kerry Dunse

Kathryn Briant

Australia

Brandon Mitchener

Belgium

Reneta Ilieva

Bulgaria

Herman Barkema

Canada

Darija

Croatia

Soha Nazmy

Egypt

Natati Fita

Mufedei Kasim

Ethiopia

Mohankumar Korlapati

Ratna Devi

Dillipkumar Mallik

Tamanna Sachdeva

Upendra Nayak

Ankit Dabra

Ratikanta Nayak

Shubham Rawat

Deepali Garg

Ratikanta NAYAK

Raja siva sankar Sahoo

Abhishek Chauhan

Shrey Aneja

Harsheen Arora

Neelesh Sharma

M Uday Shankar Nag

India

Antonella Giacomin

Italia

Ruzhdi Rexha

Agron Bytyqi

Kosovo

Fred Johnson

Liberia

Biljana Mircheska

Neda Milevska-Kostova

Bojan Trpchevski

Avram Kjiprovski

Jasminka Radoshevikj

Mirko Spiroski

Violeta Milevska

Bodan Kostov

Slavica Stavrevska

Macedonia

Maud Mwakasungula

Ellos Lodzeni

Malawi

Elizabeth Mejia

Mexico

Mohammed omar

Morocco

Myat Bhone Aung

Myanmar

Deepak K Yadav

Nepal

Mary Lynne Van Poelgeest

Robin

Netherlands

Edward Yibon

Lawrence Daniel

Folasade Lawal

Kingsley Ekwunife

Dr. Uzodinma Adirieje

Faari Usman

Adeleke Adedoyin

Mohammed Umar

Rjimra Ande

Balarabe Aliyu

Bisi Bright

Bukky Ogunsakin

Dan Abubakar

Valentine Ezeiru

Aminu Zakari

Nigeria

Ahmad Hussen Tareq

Pakistan

Reggie Drilon

Nelia Medina

Janet Paguirigan

Reynaldo Abacan

liza naranjo

Kara Alikpala

Karen Ida Villanueva

Fatima Lorenzo

Marimel Lamsin

Liberty Calla

Araceli Lanorio

Ruth

Philippines

Antonia Gama

Portugal

Matiok Anthony Madut

South Sudan

Armando Ruiz

Spain

Ksenia Baucher

Switzerland

Orajitt Bumrungskulswat

Thailand

BWAMBALE ARAFAT

BWAMBALE

Uganda

Rachel Ghitinji

Dani Mothci

Monique Franca

Judy Birch

United Kingdom

Sarah Miller

Deepa DAHAL

Elizabeth Hermsen

Nina Hill

Kathleen Arntsen

Christian Lillis

Joyce Graff

Vencislav Kurciski

Candace DeMatteis

United States

Organizations

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* Under UN Security Council Resolution 1244/99